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Week 1
Jacksonville @ Houston (-9)
Cincinnati @ Buffalo (-12)
Oakland (-2) @ Seattle
Dallas @ Arizona (-12)
San Francisco @ Detroit (-6)
New York (A) (-6) @ Kansas City
Los Angeles (A) @ Miami (-16)
Denver (-8) @ Los Angeles (N)
Minnesota (-2) @ New England
Indianapolis @ New York (N) (-8)
Tennessee @ Philadelphia (-2)
Atlanta @ Washington (-1) Game of the week
Cleveland (-10) @ Baltimore
Carolina @ Pittsburgh (-10)
Chicago (-11) @ New Orleans
Green Bay @ Tampa Bay (-11)
Week 2
San Francisco @ New York (N) (-15)
Buffalo (-1) @ Houston
Minnesota (-5) @ Detroit
Atlanta @ Cleveland (-16)
Carolina @ New Orleans (-5)
Tampa Bay (-5) @ Los Angeles (N)
Washington @ Philadelphia (-4)
Jacksonville @ Dallas (-1) Game of the week
Pittsburgh @ Cincinnati (-2)
Tennessee @ Indianapolis (-10)
New York (A) @ Miami (-5)
Los Angeles (A) @ Baltimore (-4)
New England @ Chicago (-10)
Green Bay @ Seattle (-3)
Denver (-10) @ Kansas City
Oakland @ Arizona (-4)
Week 3
New England (-4) @ Los Angeles (A)
Baltimore @ Carolina (even)
Pittsburgh @ Tampa Bay (-10)
New York (N) (-9) @ Tennessee
New Orleans @ Atlanta (-4)
Minnesota @ Buffalo (-4)
Houston (-6) @ Philadelphia
Detroit @ Dallas (even) Game of the week
Kansas City @ Jacksonville (-4)
Washington @ Indianapolis (-12)
Green Bay @ Chicago (-13)
Arizona (-3) @ Seattle
Miami @ Denver (-5)
Oakland @ New York (A) (-5)
Cincinnati @ Cleveland (-13)
Los Angeles (N) @ San Francisco (even)
Week 4
New England @ Buffalo (-9)
Green Bay @ New York (A) (-10)
Miami @ Cleveland (-4)
Carolina @ Atlanta (-6)
Arizona @ Denver (-8)
San Francisco @ Los Angeles (A) (-2)
New York (N) @ Tampa Bay (-2)
Seattle @ Los Angeles (N) (-3)
Kansas City @ Oakland (-10)
Indianapolis @ Houston (-4)
Philadelphia @ Dallas (-4)
Washington @ Jacksonville (-7)
Tennessee @ Baltimore (-3)
Cincinnati @ Pittsburgh (-4)
New Orleans @ Detroit (-7)
Chicago @ Minnesota (-1) Game of the week
Week 5
Dallas @ New York (N) (-15)
Houston (-5) @ Tennessee
Jacksonville @ Pittsburgh (-5)
Tampa Bay (-11) @ Carolina
Indianapolis @ Cleveland (-9)
Los Angeles (N) @ Oakland (-8)
New Orleans @ San Francisco (-4)
Denver @ Buffalo (-1)
New York (A) @ Minnesota (-4)
Seattle (-2) @ Washington
Cincinnati @ Baltimore (even)
Los Angeles (A) @ Kansas City (-5)
Arizona (-7) @ Philadelphia
New England @ Green Bay (even) Game of the week
Atlanta @ Chicago (-16)
Miami (-6) @ Detroit
Week 6
Oakland (-6) @ Los Angeles (A)
Denver (-11) @ San Francisco
Dallas @ Tennessee (-3)
Arizona (-8) @ Washington
Kansas City @ New England (-8)
Los Angeles (N) @ Seattle (-3)
Jacksonville @ New York (N) (-13)
Carolina @ Philadelphia (-5)
Cincinnati @ Atlanta (even) Game of the week
Detroit @ Chicago (-13)
Tampa Bay (-8) @ Baltimore
Green Bay (-1) @ New Orleans
Miami @ Minnesota (-2)
New York (A) @ Buffalo (-5)
Cleveland (-6) @ Pittsburgh
Houston @ Indianapolis (-2)
Week 7
Houston (-3) @ Jacksonville
Denver (-4) @ Indianapolis
Baltimore @ Pittsburgh (-7)
Kansas City @ Los Angeles (N) (-5)
Seattle (-1) @ Philadelphia Game of the week
New York (N) (-9) @ Dallas
Washington @ San Francisco (-5)
Minnesota @ Chicago (-5)
New England @ New York (A) (-7)
Buffalo (-6) @ Green Bay
Oakland @ Miami (-7)
Los Angeles (A) @ Arizona (-13)
Tampa Bay (-8) @ Atlanta
New Orleans @ Cincinnati (-7)
Cleveland (-10) @ Tennessee
Detroit (-3) @ Carolina
Week 8
Houston (-2) @ Cincinnati
Minnesota (-11) @ Carolina
Detroit @ Green Bay (-3)
Baltimore @ Atlanta (-3)
New Orleans @ Tampa Bay (-15)
Washington @ Chicago (-18)
San Francisco @ Dallas (-3)
Seattle @ Kansas City (-1)
Los Angeles (N) (-1) @ Los Angeles (A)
New York (N) @ Arizona (even) Game of the week
Philadelphia @ Indianapolis (-11)
Tennessee @ Jacksonville (-5)
Denver (-5) @ New England
Buffalo (-1) @ Oakland
Miami @ New York (A) (-1)
Pittsburgh @ Cleveland (-12)
Week 9
New England (-3) @ Tennessee
New York (N) (-10) @ Philadelphia
Kansas City @ Los Angeles (A) (-1) Game of the week
Washington @ Dallas (-5)
San Francisco @ Seattle (-6)
Oakland @ Denver (-9)
Miami @ Buffalo (-3)
Pittsburgh @ Houston (-7)
Cleveland (-7) @ Cincinnati
Carolina @ Green Bay (-9)
Los Angeles (N) @ Minnesota (-11)
Chicago (-1) @ Arizona
Tampa Bay (-5) @ Detroit
Atlanta @ New Orleans (-2)
Baltimore @ Indianapolis (-10)
Jacksonville @ New York (A) (-11)
Week 10
Kansas City @ Denver (-16)
San Francisco @ Los Angeles (N) (-6)
Houston (-7) @ Washington
Philadelphia @ Jacksonville (-6)
Pittsburgh (-1) @ Baltimore Game of the week
Indianapolis (-4) @ Dallas
New York (N) (-6) @ Seattle
Chicago @ New York (A) (even)
Buffalo (-3) @ New England
Green Bay @ Miami (-12)
Los Angeles (A) @ Oakland (-12)
Arizona (-6) @ Atlanta
Tampa Bay (-9) @ New Orleans
Tennessee @ Cincinnati (-6)
Carolina @ Cleveland (-19)
Detroit @ Minnesota (-11)
Week 11
Miami (-3) @ New England
Kansas City @ Buffalo (-14)
Dallas @ Seattle (-6)
Denver (-12) @ Los Angeles (A)
San Francisco @ Oakland (-11)
Philadelphia @ New York (N) (-16)
Tennessee @ Washington (-1)
New York (A) (-3) @ Pittsburgh
Cleveland (-2) @ Houston
Cincinnati (-3) @ Carolina
Green Bay @ Minnesota (-11)
Los Angeles (N) @ Arizona (-9)
Chicago @ Tampa Bay (-1)
Detroit @ Atlanta (even) Game of the week
New Orleans @ Baltimore (-4)
Indianapolis (-2) @ Jacksonville
Week 12
New York (N) (-1) @ Houston
Detroit @ Buffalo (-12)
Minnesota (-8) @ Atlanta
Cleveland (-11) @ New Orleans
Carolina @ Tampa Bay (-17)
Washington @ Los Angeles (N) (-8)
Dallas @ Philadelphia (-2)
Cincinnati @ Jacksonville (-2)
Pittsburgh (-1) @ Tennessee Game of the week
Indianapolis @ Miami (-8)
Los Angeles (A) @ New York (A) (-14)
Baltimore @ New England (-9)
Chicago (-7) @ Green Bay
Seattle @ Denver (-14)
Oakland (-4) @ Kansas City
Arizona (-6) @ San Francisco
Week 13
Jacksonville @ Cleveland (-14)
Philadelphia @ Los Angeles (N) (-7)
Indianapolis (-4) @ Tennessee
Atlanta @ Tampa Bay (-14)
Dallas @ Washington (-1)
Pittsburgh (-2) @ New Orleans
Baltimore @ Cincinnati (-6)
Los Angeles (A) @ Denver (-18)
Kansas City @ San Francisco (-2)
Minnesota @ New York (N) (-4)
Green Bay @ Detroit (-3)
Seattle @ Arizona (-9)
Houston @ Oakland (-3)
Buffalo @ Miami (-3)
New York (A) (-1) @ New England Game of the week
Carolina @ Chicago (-19)
Week 14
Washington @ New York (N) (-17)
New England @ Oakland (-5)
Jacksonville @ Indianapolis (-8)
Baltimore @ Cleveland (-16)
Tennessee @ Houston (-11)
Seattle (-3) @ Carolina
New York (A) @ Denver (-7)
Buffalo (-10) @ Los Angeles (A)
Chicago (-7) @ Detroit
Tampa Bay (-5) @ Cincinnati
Miami (-8) @ Kansas City
Atlanta @ Pittsburgh (-7)
New Orleans @ Minnesota (-15)
Philadelphia @ Green Bay (-7)
San Francisco @ Arizona (-12)
Los Angeles (N) @ Dallas (even) Game of the week
Week 15
Buffalo @ New York (A) (-1)
Seattle @ San Francisco (even) Game of the week
Dallas @ Houston (-11)
Indianapolis @ Pittsburgh (even)
Cleveland @ Denver (-4)
Oakland (-2) @ Cincinnati
Tampa Bay @ Minnesota (-3)
Baltimore @ Jacksonville (-5)
Los Angeles (N) @ New York (N) (-12)
Arizona (-5) @ Kansas City
Tennessee @ Los Angeles (A) (-2)
New Orleans @ Carolina (-1)
Philadelphia @ Washington (-2)
Detroit @ New England (-6)
Atlanta @ Green Bay (-6)
Chicago @ Miami (-2)
Week 16
New England @ Miami (-9)
New York (A) (-4) @ Detroit
Cleveland @ Tampa Bay (-1)
Cincinnati @ Indianapolis (-7)
Houston (-5) @ Baltimore
Pittsburgh @ Kansas City (even)
Buffalo @ Chicago (-4)
Arizona (-3) @ Los Angeles (N)
Minnesota (-5) @ Green Bay
Atlanta @ Carolina (even) Game of the week
Dallas @ New Orleans (-2)
Los Angeles (A) @ Seattle (-7)
Denver (-3) @ Oakland
Philadelphia @ San Francisco (-4)
New York (N) (-11) @ Washington
Jacksonville @ Tennessee (-1)